Increase GLP-1 Levels
Increase GLP-1 Levels
Discover how to naturally increase GLP-1 levels through gut health, according to microbiologist Colleen Cutcliffe, Ph.D. Learn about the role of Akkermansia muciniphila and key dietary changes to boost metabolism and regulate blood sugar.
Introduction:
GLP-1 is a hormone essential for blood sugar regulation, energy metabolism, and appetite control. While drugs like Ozempic mimic its effects, your own gut microbiome can naturally stimulate GLP-1 production—if supported correctly. Microbiologist Colleen Cutcliffe, Ph.D., explains how.
What Is GLP-1 & Why It Matters
GLP-1 (Glucagon-like peptide-1) is released after meals and tells your brain you’re full. It helps your body manage sugar and supports overall metabolic function. Low GLP-1 can lead to poor energy, weight gain, and blood sugar crashes.
The Microbiome–Metabolism Connection
Your gut microbiome is deeply linked to your metabolism. Imbalances in gut bacteria can cause:
- Fatigue after meals
- Difficulty losing weight
- Blood sugar spikes
- Food sensitivities
Cutcliffe says: if your metabolism feels “off,” your gut might be the root cause.
The Two Key Bacterial Strains That Boost GLP-1
- Akkermansia muciniphila
- Strengthens the gut lining
- Prevents leaky gut and inflammation
- Linked to better outcomes in weight loss and even cancer therapies
- Clostridium butyricum
- Supports butyrate production
- Enhances GLP-1 secretion
How To Naturally Boost Akkermansia & GLP-1
1. Eat More Fiber & Polyphenols:
Fiber and plant compounds create the perfect environment for GLP-1-boosting microbes.
Best foods:
- Leafy greens: Spinach, kale, artichokes
- Fruits & polyphenol-rich foods: Pomegranate, raspberries, cranberries
- Prebiotic foods: Onions, garlic, bananas, oats
2. Take Targeted Probiotics:
Supplements like Pendulum’s Akkermansia muciniphila can directly increase this keystone strain, backed by clinical studies.
The Bottom Line
Rather than relying solely on medications, supporting your gut with the right foods and probiotics may naturally increase GLP-1, improving metabolism, reducing cravings, and helping with weight management. As science continues to uncover the power of the microbiome, small dietary steps may yield big metabolic results.